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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GSK3A
All Species:
17.58
Human Site:
T411
Identified Species:
27.62
UniProt:
P49840
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49840
NP_063937.2
483
50981
T411
D
E
L
R
C
L
G
T
Q
L
P
N
N
R
P
Chimpanzee
Pan troglodytes
XP_530044
483
51007
T411
D
E
L
R
C
L
G
T
Q
L
P
N
N
R
P
Rhesus Macaque
Macaca mulatta
XP_001104964
483
50993
T411
D
E
L
R
C
L
G
T
Q
L
P
N
N
R
P
Dog
Lupus familis
XP_852706
441
48143
T369
D
E
L
R
C
H
G
T
Q
L
P
N
N
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q2NL51
490
51642
A412
D
E
L
R
R
L
G
A
Q
L
P
N
D
R
P
Rat
Rattus norvegicus
P18265
483
51008
T411
D
E
L
R
S
L
G
T
Q
L
P
N
N
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416557
433
48108
K362
E
L
R
D
P
N
V
K
L
P
N
G
R
E
K
Frog
Xenopus laevis
NP_001083752
420
46885
L348
D
E
L
R
D
P
N
L
K
L
P
N
G
R
E
Zebra Danio
Brachydanio rerio
NP_001038386
462
50821
H391
S
P
L
Q
A
C
A
H
A
F
F
D
E
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18431
1067
114422
N899
D
E
L
R
M
E
G
N
H
T
L
P
N
G
R
Honey Bee
Apis mellifera
XP_392504
434
48445
R363
G
T
R
L
P
N
G
R
E
L
P
P
L
F
N
Nematode Worm
Caenorhab. elegans
Q9U2Q9
362
40864
A291
V
F
R
V
H
T
P
A
E
A
I
D
L
I
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
P223
I
F
R
I
L
G
T
P
N
E
Q
S
W
P
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZD5
410
46056
R337
E
A
V
D
L
V
S
R
L
L
Q
Y
S
P
N
Baker's Yeast
Sacchar. cerevisiae
P38615
370
42986
L299
D
D
Q
T
V
E
F
L
A
D
V
L
K
Y
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.7
85.5
N.A.
93.8
97
N.A.
N.A.
67.9
67.4
71.8
N.A.
33.4
64.1
55.2
N.A.
Protein Similarity:
100
99.7
99.7
86.3
N.A.
95.5
97.7
N.A.
N.A.
74.9
74.5
77.6
N.A.
38
75.1
63.7
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
80
93.3
N.A.
N.A.
0
53.3
6.6
N.A.
40
20
0
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
N.A.
6.6
60
20
N.A.
40
26.6
13.3
N.A.
Percent
Protein Identity:
N.A.
24.4
N.A.
52.8
40.7
N.A.
Protein Similarity:
N.A.
38.1
N.A.
63.7
55.4
N.A.
P-Site Identity:
N.A.
0
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
33.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
7
0
7
14
14
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
27
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
60
7
0
14
7
0
0
0
0
7
0
14
7
0
7
% D
% Glu:
14
54
0
0
0
14
0
0
14
7
0
0
7
7
7
% E
% Phe:
0
14
0
0
0
0
7
0
0
7
7
0
0
7
0
% F
% Gly:
7
0
0
0
0
7
54
0
0
0
0
7
7
7
7
% G
% His:
0
0
0
0
7
7
0
7
7
0
0
0
0
0
0
% H
% Ile:
7
0
0
7
0
0
0
0
0
0
7
0
0
7
0
% I
% Lys:
0
0
0
0
0
0
0
7
7
0
0
0
7
0
7
% K
% Leu:
0
7
60
7
14
34
0
14
14
60
7
7
14
7
0
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
14
7
7
7
0
7
47
40
0
14
% N
% Pro:
0
7
0
0
14
7
7
7
0
7
54
14
0
14
40
% P
% Gln:
0
0
7
7
0
0
0
0
40
0
14
0
0
0
0
% Q
% Arg:
0
0
27
54
7
0
0
14
0
0
0
0
7
47
14
% R
% Ser:
7
0
0
0
7
0
7
0
0
0
0
7
7
0
7
% S
% Thr:
0
7
0
7
0
7
7
34
0
7
0
0
0
0
0
% T
% Val:
7
0
7
7
7
7
7
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
7
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _